What does measles actually do?

first_img Number of measles infections each year from 2001 through 2014. Part of the reason for the resurgence is a rise in the number of parents who refuse to vaccinate their children against the virus. Despite an overwhelming amount of scientific and medical evidence demonstrating both the safety and efficacy of the measles vaccine, some parents refuse to vaccinate their children for reasons of personal belief. The problem is compounded because many like-minded parents are geographically clustered. For the entire state of California, the vaccine refusal rate is only 2.6%, indicating that most citizens are cognizant of the benefits of immunization. However, a recent study of pediatric health records revealed that in some areas the vaccine refusal rate is as high as 13.5%. Other factors such as a lack of time, education, or money can cause parents to inadvertently fall behind on their children’s immunizations.Disneyland provided an ideal starting point for an epidemic. In such a crowded atmosphere, a single infected individual might come in contact with hundreds or thousands of people in a day. Even if 90% of people are immunized, the virus’s high infectivity will allow it to spread through the population by jumping between susceptible individuals.How can I protect my children from getting measles?Get them vaccinated. CDC center_img The United States is now experiencing what promises to be one of the worst outbreaks of measles since the virus was declared eliminated from the country in 2000.  It began in early January at Disneyland Resort in Anaheim, California, and has since spread to 14 states and infected 84 people, according to the U.S. Centers for Disease Control and Prevention (CDC). Measles, caused by a paramyxovirus from the genus Morbillivirus, is one of the most contagious diseases in the world, infecting more than 90% of susceptible hosts that come in contact with an afflicted individual. In the absence of widespread vaccination, the average person with measles will infect an average of 12 to 18 other people; in contrast, Ebola is typically transmitted to 1.5 to 2.5 people. Children, in particular, are more likely to experience complications as a result of a measles infection. Although the overall mortality rate for children who get measles is only between 0.1% and 0.2%, as many as one out of every 20 children will also develop pneumonia. The disease symptoms can be managed with common anti-inflammatory drugs, hydration, and rest, but like many other viral illnesses, there is no cure and antibiotics will have no effect. Death rates are much higher in developing countries.What does measles do to the immune system?Measles virus is spread from person to person through the air in coughed-out aerosolized droplets that are inhaled. The virus typically first comes in contact with host lung tissue, where it infects immune cells called macrophages and dendritic cells, which serve as an early defense and warning system. From there, the infected cells migrate to the lymph nodes where they transfer the virus to B and T cells. A surface protein on these white blood cells, known as CD150, serves as the virus’s point of entry during this critical step. The infected B and T cells then migrate throughout the body releasing virus particles into the blood. The spleen, lymph nodes, liver, thymus, skin, and lungs are eventual destinations for the virus. In rare instances (about one in 1000 cases), the virus can cross the blood-brain barrier and cause dangerous swelling of the brain; infection of lung cells causes a hacking cough that keeps the virus circulating in the population.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)Why does measles cause a rash?One of the classic presentations of a measles infection is a rash characterized by flat red blotches that starts on the face and moves down the body all the way to the feet over a few days. The rash is a symptom of inflammation occurring in the skin. As the virus travels in the blood, it infects capillaries in the skin. Immune cells detect the infection and respond by releasing chemicals such as nitric oxide and histamines, which destroy the viral invaders and call other immune cells into action. These same chemicals, however, cause swelling and damage to host cells, resulting in the often itchy skin rash, which usually occurs concurrently with a fever that can reach as high as 40°C. Why is measles back?Measles has actually been back. Last year was one of the worst years in recent history for the United States: CDC reported 644 cases from 23 separate outbreaks during 2014; between 2001 and 2013, no single year saw more than 250 cases. (Because measles was declared “eliminated” in the United States in 2000, outbreaks have been triggered by virus “imported” from other countries, which then finds an unvaccinated person.) With 84 people infected already in 2015, things are not off to the best start.last_img read more

Indian fans buying more World Cup tickets than English – despite India not qualifying

first_imgAlmost 400,000 World Cup tickets have been sold in the latest FIFA allocation, but England fans have remained reticent buyers.The latest sales window opened on March 13 and saw a total of 394,433 tickets purchased.Hosts Russia accounted for the vast majority of that number, with 216,134 going to home supporters, with the North and South America the next best market.Read it at Evening Echo Related Itemslast_img

Thangavelu Mariyappan returns home to heros welcome

first_imgChennai, Sep 23 (PTI) Thangavelu Mariyappan, who won a gold medal at the Paralympics in Rio de Janeiro, returned home to a heros welcome here today. Tamil Nadu Ministers for School Education, Sports and Youth Welfare, K Pandiarajan, Rural Industries Minister P Benjamin along with several senior government officials received Mariyappan at the airport here, officials said. Mariyappan, hailing from Periyavadagampatti village near Salem in western Tamil Nadu, won the gold in the T-42 High Jump event with a best effort of 1.89m, leaving behind world champion Sam Grewe of the USA, who registered 1.86 m. The T-42 classification is for athletes with lower limb deficiency, leg length difference, impaired muscle power or impaired range of movement. Mariyappan, who was five when his right leg was crushed by a speeding bus, joined Murlikant Petkar (1972, swimming) and Devendra Jhajharia (2004, javelin throw) in the Indian Paralympics gold club. Hailing his feat, Chief Minister Jayalalithaa had announced a cash prize of Rs. 2 crore for Mariyappan. PTI CORR VIJ VS AH PDSlast_img read more

Men’s Open Squad Inspire Parkes Juniors

first_imgAs part of the weekend, the squad helped coach Parkes’ junior teams who will take part in the New South Wales Junior State Cup later this month. Parkes Touch Association President, Al Gersbach, says it was an enjoyable experience for all involved. “We got a lot out of it from a coaching point of view and the kids got a lot more out of it. They thoroughly enjoyed themselves. We had a dinner on the Saturday night and the comment I made was that a few times during the day I got the opportunity to stand there and look around and see everyone’s expressions and all of the Australian players were laughing and doing stuff with the kids and the kids were having a ball, they were over the moon. They were all laughing and having fun and the Aussie guys did an absolute fantastic job,” Gersbach said. It is the second time that the squad has trained in Parkes in recent years, following their first training camp at Pioneer Oval in October 2009. Gersbach says that there are plenty of benefits of having the squad comes to Parkes and hopes it can happen again in the future. “It’s good that we’ve got that association with the guys after the first one we had, it’s just grown from that. A lot of friendships were made then and I think they continued from there, especially with the kids, they knew most of the Aussie players when they turned up. For the new kids, they were just over the moon that there were Australian players standing there in front of them.”“I can’t speak highly enough of what they’ve done for us, the benefits we received, and the squad from the sound of it thoroughly enjoyed coming out here too. They were very professional in the way they went about things,” Gersbach said. Close to 150 players and officials from Parkes will travel to Wollongong for the Junior State Cup later this month and the teams are looking forward to the challenge following the help from their new friends. “I’m actually the coach of the under 12’s boys team and the improvement that came from them after the weekend, we trained again on Monday after the guys left on Sunday and the improvement was 50 per cent better than before.”Thank you to Fiona Lovett from Parkes Touch Association for providing the photos. More photos can be found on the Touch Football Australia Facebook page as well as the High Performance part of this website. Please click on the following links:http://www.sportingpulse.com/assoc_page.cgi?c=14-3780-0-0-0&a=PHOTOGAL_Vhttp://www.facebook.com/pages/Touch-Football-Australia/384949403384last_img read more

ESPN’s Football Power Index Strength Of Schedule Rankings Are SEC-Heavy

first_imgESPN’s pre-season Football Power Index (FPI), defined as “a measure of team strength that is meant to be the best predictor of a team’s performance going forward for the rest of the season” has debuted. The rankings are compiled based off the results of 10,000 simulations. One of the categories you can rank teams in order of is remaining strength of schedule. Since the 2015 season hasn’t begun, the FPI strength of schedule rankings represent which teams have the toughest slates this year. Alabama tops the FPI strength of schedule rankings, and the top 20 is not surprisingly SEC-heavy. Twelve of the 20 programs are members of the SEC. ESPN SOS RankingESPN SOS RankingThe full FPI rankings are available here.last_img

This College Football Program Always Has A Great Season When There’s A Triple Crown Winner

first_imgA general view of Notre Dame's football field.SOUTH BEND, IN – SEPTEMBER 25: A general view of the opening kick-off between the Notre Dame Fighting Irish and the Stanford Cardinal at Notre Dame Stadium on September 25, 2010 in South Bend, Indiana. Stanford defeated Notre Dame 37-14. (Photo by Jonathan Daniel/Getty Images)Yesterday, Justify captured the Belmont Stakes to become the 13th Triple Crown winner in American horse racing history. Justify joins American Pharoah (2015) as the most recent Triple Crown winners.On the surface, there may not be much connection between horse racing and college football, but one program seems to always have a big season a few months after a horse wins the Triple Crown.Notre Dame has a major tradition of performing well in Triple Crown years. That’s good news for Irish fans.This stat, unearthed by ND alum and longtime Clemson football SID Tim Bourret, shows the tie between the Irish and the best racehorses America has to offer.Count on a good football season for Notre Dame in 2018. Years there has been a Triple Crown winner in Horse Racing, the Fighting Irish are a combined 108-10-5 (90 percent) with 5 National Championships, 6 undefeated seasons and 7 top 4 finishes.— Tim Bourret (@TimBourret) June 10, 2018In 2015, Notre Dame went 10-2 in the regular season and earned a trip to the Fiesta Bowl. That was after American Pharaoh snapped a 27-year Triple Crown drought.Can they duplicate or even top that feat this year? The schedule is tough, with an opening game against Michigan, trips to USC and Virginia Tech and other home games against Florida State and Stanford.But the Irish should be particularly strong defensively, and if the offense takes a step forward under quarterback Brandon Wimbush, the ingredients for another 10-win season are there.Plus, it seems like Notre Dame has history on its side.last_img read more

New Website Puts Data on the Map

first_img A new Internet site launched today, June 16, will make it easierfor people to find high quality Nova Scotia geographic data. The GeoNOVA web portal was launched during a one-day workshop inHalifax, that explored the future of the geomatics industry inAtlantic Canada. Geomatics, the gathering, storage, analysis and use ofgeographically referenced information, is an important industryin this region. This information has a variety of uses, includingmapping, municipal planning, transportation infrastructuremanagement, business planning, natural resource stewardship andagriculture. Service Nova Scotia and Municipal Relations deputy minister GregKeefe unveiled the new web portal (www.geonova.ca) to about 100workshop attendees. “The offerings are a mix of free information and web-basedsubscription services like Property Online,” said Mr. Keefe. “The general public will find the site a good resource, as well,”he added. “For example, one can order all sorts of maps online;topographical maps for hikers, navigation and coastal charts forsailors and aeronautical charts for pilots.” A cornerstone of the province’s GeoNOVA program, the portal linkscollections of information held by federal, provincial andmunicipal offices across the province and groups them into easyto search categories. The GeoNOVA portal is a 50-50 cost-sharing partnership betweenthe government of Nova Scotia and Natural Resources Canada GeoConnections program. The Halifax and Cape Breton regionalmunicipalities are also important GeoNOVA stakeholders andsupporters. “GeoNOVA is another example of Service Nova Scotia and MunicipalRelations commitment to online services,” said Mr. Keefe. “Fromrenewing vehicle registration to accessing high end geographicinformation, we’re delivering the services people want, online,when and where they want them.” SERVICE N.S./MUNICIPAL RELATIONS–New Website Puts Data on theMaplast_img read more

Why Melanie Jolys Creative Canada is good news for Canadian screenwriters and

first_imgREAD MORE LEAVE A REPLY Cancel replyLog in to leave a comment WHEN HERITAGE MINISTER Mélanie Joly delivered her Creative Canada vision statement last Thursday in Ottawa I was extremely pleased on behalf of Canadian screenwriters — at last, a vision for Canada that puts creators at the centre.While “creator” can mean many things, when it comes to screen-based entertainment, it means the showrunners and screenwriters that the Writers Guild of Canada represents. However, I wasn’t only pleased for WGC members because I also felt genuine hope — for the first time in a long time (remember the long, Canadian-arts-and-culture-dry years of the Harper government?) — for Canada. The direction of Creative Canada clearly is designed to give Canadian audio-visual entertainment (a form of entertainment that’s arguably the most popular cultural force of our day) a far better chance of being seen around the world than it has had in a very long time.Of course, the news that Netflix is putting in $500 million over five years into Canadian programming and opening a Canadian production office has been the focus of most of the media coverage and of the attention of industry colleagues. There’s more to the announcement than that, but let’s start with a closer look at that $500 million. That’s one hundred million dollars a year. That’s roughly the average spending by each of Bell Media and Corus Entertainment, respectively, on programmes of national interest (PNI), things like drama, comedy, documentary and some children’s programming, per year, over the past few years. That’s right, Netflix is kicking in as much money per year as each of these two Canadian broadcasters, who have benefited from corporate protections and received subsidies, and yet not produced a significant volume of original Canadian programming. Advertisement Facebook Login/Register With: Advertisement Twitter Advertisementlast_img read more

Djokovic eyes record sixth Indian Wells Masters title

first_imgIndian Wells (United States): Doubt is a distant memory for Novak Djokovic as the world number one returns to Indian Wells on top of the tennis world, one year after his shock loss to qualifier Taro Daniel. Djokovic is making his first start since winning his third Grand Slam title on the trot at the Australian Open in January. He said he wasn’t fully recovered from elbow surgery when he opted to compete in the California desert last year, but it’s not a decision he regrets given the events that followed in 2018. Also Read – Dhoni, Paes spotted playing football together “I definitely wasn’t ready to compete at this level last year,” the Serb said Thursday as he looked forward to his title defense in the elite Masters series event. “I was kind of convincing myself that I was, but I truly wasn’t. “I know most of my team members at the time were against me playing in Indian Wells and Miami because it was too early after the surgery. “I could have, should have made a different decision, but I believe it also taught me some valuable lessons that helped me to create amazing results in the next seven, eight months and get from 22 in the world to No. 1 in the world in less than six months.” Also Read – Andy Murray to make Grand Slam return at Australian Open Djokovic would cement his return with a Wimbledon title and follow that with a US Open crown. He dominated Rafael Nadal in January’s Australian Open title and must be favored for a sixth Indian Wells crown — which would see him break the record he currently shares with fourth-seeded Roger Federer. Djokovic will open in the second round against 128th-ranked American Bjorn Fratangelo, who beat fellow qualifier Elias Ymer of Sweden 4-6, 6-2, 6-2. He could face a dangerous third-round clash with Australian Nick Kyrgios, seeded 31st, who is coming off his first title in more than a year in Acapulco last week. Kyrgios will take on Philipp Kohlschreiber in the second round after the German veteran dispatched France’s Pierre-Hugues Herbert 6-4, 6-0. The Australian beat Nadal, former world number three Stan Wawrkina, ninth-ranked John Isner and number three Alexander Zverev on route the title in Mexico. He also holds a 2-0 career record against Djokovic, including a straight-sets victory over the Serb star in Indian Wells two years ago. “If I get a chance to play against him … I’ll look forward to that because he’s in-form,” Djokovic said. “On the other hand, I started the season very well. “I hope I can restart here where I stopped in Australia.” In other first-round matches Thursday American Sam Querrey defeated Italian Matteo Berrettini 7-6 (7/5), 2-6, 6-4 to line up a meeting with 13th-seeded Milos Raonic — a rematch of their quarter-final here last year won by the Canadian. Veteran Ivo Karlovic defeated Australian Matthew Ebden 7-6 (7/3), 7-6 (7/3) to line up an all-Croatian clash with 11th-seeded Borna Coric. Canadian 18-year-old Felix Auger-Aliassime, ranked 58th in the world, defeated Britain’s Cameron Norrie 6-3, 6-2 to book a meeting with rising Greek star Stefanos Tsitsipas.last_img read more

SEBI bars Leela sale to Brookfield

first_imgMumbai: Market regulator SEBI came down forcefully against Hotel Leelaventure, barring it from selling its four high-profile hotels and other assets to Canadian investment fund Brookfield Asset Management. In the ongoing saga, the dramatic development came after ITC moved the National Company Law Tribunal (NCLT) against Leela alleging “oppression and mismanagement”. ITC also claimed that the deal between Leela and Brookfield was against the company’s and shareholders’ interests. SEBI has received representations from ITC on the matter and mentioned this in its letter to Leela. Also Read – Thermal coal import may surpass 200 MT this fiscal ITC’s plea was mentioned before the Mumbai bench of the NCLT, which posted the matter for hearing on Wednesday, Hotel Leelaventure said in a regulatory filing on Tuesday. “Representations/allegations against HLVL, as received by Sebi in relation to the issue, concerns the interest of the investors in the security market… While representations are being examined by Sebi, in paucity of time involved and in the interest of investors in securities, you are advised to ensure that none of the transactions proposed in the postal ballot notice dated March 18 are acted upon till further directions from Sebi,” Hotel Leelaventure said in the filing. Also Read – Food grain output seen at 140.57 mt in current fiscal on monsoon boost In conjunction with the petition to NCLT, ITC also filed two applications seeking a waiver of the requirement of the minimum threshold of 10 per cent shareholding, it added. ITC holds 7.92 per cent stake in Hotel Leelaventure. The embattled hospitality group owned by the Nairs on March 18 had announced the sale of its four hotels located in Bengaluru, Chennai, Delhi and Udaipur, and a land parcel in Agra to Canadian investment fund Brookfield for Rs 3,950 crore. It also sought shareholders’ approval, the voting for which is scheduled to end on April 24.last_img read more

Germanys Siemens appoints longtime finance chief Joe Kaeser as CEO replacing Peter

Germany’s Siemens appoints longtime finance chief Joe Kaeser as CEO, replacing Peter Loescher AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email by Geir Moulson, The Associated Press Posted Jul 31, 2013 5:48 am MDT BERLIN – Siemens appointed finance chief Joe Kaeser as its new chief executive on Wednesday, handing a manager with over 30 years’ experience at the industrial conglomerate the task of improving its fortunes after missed profit targets led to the departure of predecessor Peter Loescher.Siemens AG said its supervisory board unanimously chose the 56-year-old Kaeser, who will take office Thursday. It said a new chief financial officer will be appointed “in due course.”It added that Loescher would leave the board “by mutual agreement.” The company had said Saturday night that the supervisory board would meet Wednesday to decide on his departure — a terse announcement that was followed by media reports of infighting.The prospect of trouble even prompted Chancellor Angela Merkel to express concern. Spokesman Georg Streiter said earlier this week the German leader considered it important that the company — a “flagship” of German industry — return to “calm waters.”Munich-based Siemens makes industrial machinery such as power generation and transmission equipment, high-speed trains, and medical diagnostic scanners. It has 370,000 employees, including 56,500 in the United States, and is active in 190 countries.Last Thursday, the company said it would miss its 2014 goal of a 12 per cent profit margin, blaming “lower market expectations.”“During the past week I came to the conclusion that the foundation of trust necessary for me to remain was lacking,” Loescher said in a statement explaining his decision to offer his resignation. He had a contract through 2017.“This company is on the right course,” he added, wishing his successor “good luck and much success.”Kaeser, unlike Loescher, has spent his career with Siemens, which he joined in 1980. He has been chief financial officer since May 2006.“Our company is certainly not in crisis, nor is it in need of major restructuring,” Kaeser said. “However, we’ve been too preoccupied with ourselves lately and have lost some of our profit momentum vis-a-vis our competitors.”He pledged “to put Siemens back on an even keel and create a high-performance team” and said that, by this fall, Siemens will “address the medium-term prospects and our vision for the company.”Siemens said shortly after announcing the leadership change that its net profit rose 43 per cent in the April-June period, its fiscal third quarter, after it spun off its lossmaking light bulb business. Net earnings were up to 1.1 billion euros ($1.46 billion) from 770 million euros a year earlier, when light-bulb business Osram cost Siemens 354 million euros.However, other measures of profit sagged as the company took charges totalling 436 million euros for a restructuring program aimed at restoring its profit levels and a 91 million euros charge related to inspecting and refitting wind turbine blades.Siemens’ profit margin fell to 6.5 per cent from 9.2 per cent a year earlier, while revenues slipped 2 per cent to 19.25 billion euros. But the company reported a 19 per cent rise in new orders to 21.14 billion euros, thanks largely to a major British train contract.Siemens shares were 0.8 per cent lower at 80.01 euros in Frankfurt trading after the announcements.Loescher, a company outsider hired in 2007 from drug company Merck & Co., Inc., helped Siemens move past a major corruption scandal.Siemens agreed to pay more than $1 billion in fines in Germany and the United States, for, among other charges, allegedly giving customers payments to secure business, especially internationally. Supervisory board chairman Gerhard Cromme said that “Peter Loescher restored Siemens’ high reputation.”___AP Business Writer David McHugh contributed from Frankfurt. read more

Weak results from CSX Citi drag US stocks mostly lower Best Buy

AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email Weak results from CSX, Citi drag US stocks mostly lower; Best Buy plunges on sales decline NEW YORK, N.Y. – Stocks are ending mostly lower after several companies turned in disappointing earnings news, including Best Buy, Citigroup and the railroad operator CSX.The Dow Jones industrial average fell 64 points, or 0.4 per cent, to 16,417 Thursday.The Standard & Poor’s 500 index fell two points, or 0.1 per cent, to 1,845. The Nasdaq composite edged up almost four points, or 0.1 per cent, to 4,218.Best Buy plunged 29 per cent after the electronics retailer reported disappointing holiday sales, raising questions about whether it can turn its fortunes around.A weak earnings forecast from CSX late Wednesday dragged that stock and other railroads lower. CSX dropped 7 per cent.Nu Skin, a skin care and nutritional products company, plunged 39 per cent after Chinese state media reported that authorities there were investigating its business practices. by The Associated Press Posted Jan 16, 2014 2:22 pm MDT read more

Serbia at the Olympics Spain easily beats Poland

Serbia is the last team that will play the Olympic Games 2012. They did what was needed from them, beating Algeria with 26:18 (15:10), while the Polish had a nightmare game against Spain, and a disastrous result, losing 22:33 to the host team. The Spanish dominated from the beginning managing to make a huge distance even in the first half, and then it became known that Poland will miss the train to London, and it’s now the Serbs that will be taking it. ← Previous Story Poland or Serbia at the Olympics? Valero Rivera: “We always play to win” Next Story → Champions League (W): Buducnost-Gyori in the final!

iFixit teardown the new iMac 215

first_imgiFixit didn’t take long to get their hands on one of the new iMacs and decided to dismantle it in short order.The model in question is the 21.5″ sporting a 2.5GHz Intel Core i5-2800S processor with 6MB Intel Smart Cache, 4GB RAM, and an AMD Radeon HD 670M GPU. For storage, Apple used a 500GB WD Caviar Blue drive. It’s an update mainly to give the line a much-needed performance boost as can be seen from those components.As for the iMac itself, iFixit say this is pretty much just like the previous model, which unfortunately means getting inside is not the easiest of tasks. The display glass is held on magnetically meaning suction cups are your best bet for removing it without damaging the glass. Then there’s a bunch of Torx screws to remove in order to lift the display panel off the front bezel. Once that’s done you can gain access to all the components in the back casing.If that hasn’t scared you off opening up your $1199+ iMac then things get a lot easier from there. The RAM, hard drive, and optical drives are easy to locate and switch out. There’s also a free bay for adding an SSD which is an option Apple offer of some models.If you want to replace the CPU or GPU, however, the logic board has to be removed and some warranty stickers broken meaning no free Apple repairs. With the Core i5 chip and a Radeon HD 670 I doubt anyone will want to go this far as you have a lot of performance available by default.The good news is Apple has done a solid job of cooling both the CPU and GPU. Each has the right amount of thermal paste applied and each chip has a separate heatsink and cooling units. You may remember the recent MacBook Pro teardown raised a concern about excessive thermal paste, but that is not the case with the iMac. The GPU also has four Hynix 1Gb GDDR SDRAM chips (512MB total RAM) next to it being cooled by the same heatsink.iFixit give the iMac a 7 out of 10 repairability rating. So if you do want to save some money and upgrade the RAM or hard drive yourself, it’s not going to be too tough as long as you have those suction cups handy for the glass removal.Read more at iFixitlast_img read more

Mucoviscidose un espoir porté par une molécule

first_imgMucoviscidose : un espoir porté par une moléculeUne société américaine a mis au point une molécule qui aurait parfaitement réagi auprès de patients atteints de la mucoviscidose. Une nouvelle qui apporte de l’espoir alors que la maladie ne connait pour le moment aucun traitement curatif.La mucoviscidose est une maladie génétique qui touche notamment les voies respiratoires et le système digestif. Si elle n’est pas contagieuse, il n’existe pour le moment aucun traitement permettant de la soigner. Aujourd’hui, un espoir est donné par une société américaine qui a mis au point une molécule dans le cadre d’un traitement inédit. Testée sur plusieurs patients atteints d’une forme rare de la maladie, la molécule aurait permis d’obtenir de bons résultats. Une bonne nouvelle pour l’association Vaincre la mucoviscidose qui a expliqué au Télégramme : “C’est une avancée majeure. Ça nous donne un véritable espoir”. De son côté, le responsable du centre de ressources et de compétences de la mucoviscidose basé à Roscoff(29), Gilles Rault renchérit auprès du journal : “C’est la première fois qu’une molécule corrige une mutation et fait diminuer le taux de sel dans la sueur. C’est la première fois qu’on a des effets significatifs”.La compagnie Vertex Pharmaceuticals a dévoilé les résultats de son étude sur la molécule la semaine dernière, précisant bien qu’elle ne concerne que les porteurs de la mutation G551D, une forme de la maladie qui ne touche que 1% des patients atteints de la mucoviscidose. Si les résultats sont confirmés, un médicament pourrait arriver sur le marché d’ici la fin de l’année. Mais les malades et associations préfèrent toutefois rester prudents pour le moment. Le 28 février 2011 à 17:53 • Emmanuel Perrinlast_img read more

Highranking Larch Corrections Center worker focus of probe

first_imgThe Washington State Department of Corrections asked Washington State Patrol to investigate a union claim against a high-ranking employee at Larch Corrections Center.Teamsters Local 117, a union representing workers at Larch Corrections Center, last month filed a grievance over what it says is threatening behavior toward bargaining unit members by Dale Caldwell, Larch Corrections Program Manager.Members independently took a vote of no confidence over hostility in the workplace, said Paul Zilly, union spokesman.The accusations relate to Caldwell’s treatment of employees.Selena Davis, spokeswoman for the state Department of Corrections said the organization received the no-confidence petition in early March. Davis said it is typical for the department to ask for a third party, in this case WSP, to investigate these types of claims.The complaints are just allegations at this point, Davis said. DOC will wait for the results of the investigation to determine what, if any, disciplinary action needs to take place.Caldwell declined to comment, Davis said.last_img read more

New icebreaker wont have much time for the Arctic says Coast Guard

first_imgHouse Transportation Chairman Peter DeFazio, D-Ore, said that’s a concern for President Trump. A White House spokeswoman did not respond to an email asking about the president’s views on the icebreaker contract. In April, the government awarded a contract for up to three icebreakers to VT Halter Marine, a shipyard in Mississippi. Halter recently released some design details. The 460-foot hull will be able to break ice up to eight feet thick. It will accommodate 186 people for up to 90 days at a time. The Coast Guard expects to launch the first of three new icebreakers in 2024, but don’t expect to see much of it in Alaska. Coast Guard Commandant Karl Schultz said Tuesday the primary duty of the first icebreaker will be in the Antarctic, not the Far North. The new icebreaker’s essential mission will be to clear a path for supply ships serving the McMurdo Station. It takes more than 100 days to get to Antarctica, which would leave little time for trips to the Arctic. Schultz isn’t taking that lightly. He said physical presence on Arctic waters is vital for national security. The shipbuilder says it will deliver the third icebreaker by 2027. “When I was at the White House a few weeks ago, the president was quite upset at the price tag per ship,” DeFazio said at the hearing. “Until that second or third (polar) security cutter, we won’t really have much of a game up there, in terms of presence,” Adm. Schultz told a U.S. House Transportation subcommittee. “In the polar regions, presence equals influence,” he said. “And your Coast Guard is the sole surface presence protecting our rights and projecting sovereignty.” Schultz said the cost is expected to total $1.9 billion for the three ships. Artist rendering of the VT Halter Polar Security Cutter design. (Illustration: VT Halter Marine / Designer: Technology Associates, Inc.)last_img read more

Spice Girls Bus From Spice World Movie Is Now an Airbnb Rental

first_img Here’s a chance for Spice Girls fans to spice up their lives: The iconic Union Jack-painted bus that featured in the 1997 Spice Girls movie Spice World is now listed as accommodation on Airbnb.The Spice Bus, which comes complete with pink Union Jack cinema chairs, vintage 90s memorabilia, and bold interiors, will be located in the heart of Wembley Park in London, where guests will be able to stay overnight on June 14 and 15 for £99 (around $126).The renovated living area of the bus also features a very Instagram-worthy ‘Girl Power’ neon light installation. A dressing area is located upstairs, where there’s an adjoining bedroom, fitted with a striking animal-print carpet, and comfy bedding for three guests who get to call the Spice Bus home for the night.The living area aboard the Spice Bus. (Photo Credit: Matt Alexander / PA Wire)The Airbnb host is a mega-fan named Suzanne Godley.“When my boss mentioned that he was considering buying the Spice Bus I was desperate to be a part of its renovation,” she told Airbnb. “We’ve worked hard over the past few months to turn the bus into a home, in keeping with its legacy, and I’m so excited to open it up to the public with the support of Airbnb. Being part of this project has been like a dream come true and I can’t wait to meet other Spice Girls fans through this experience.”The bedroom aboard the Spice Bus, which can accommodate three guests. (Photo Credit: Matt Alexander / PA Wire)Of course, the Spice Bus comes with rules:No petsMaximum three guestsNo smoking90s dress codeDouble denim permittedGirl Power essentialSelfies in the driver’s seat encouragedCompulsory rendition of ‘Goodbye’ on check outBook the Spice Bus on Airbnb here.More on Geek.com:Google Combines Trip Planning Features Under One RoofThis $5 Million Solar-Powered Yacht Cruises in ‘Pure Silence’This Futuristic Mini Yacht Fits 12 People and Travels Up to 70 MPH Airbnb For Work Simplifies Business TravelAirbnb’s Oscar Mayer Wienermobile Rental Is a Hot Dog Lover’s Paradise Stay on targetlast_img read more